Comforting, creamy butternut squash lasagna layered with sage-infused sauce, ricotta, spinach, and gooey mozzarella. A cozy fall favorite that comes together easily for weeknights or entertaining.
3tablespoonsall-purpose flourfor thickening the sauce
3cupswhole milkroom temperature if possible
0.5cupsvegetable brothto help puree the squash
2cupsricotta cheese
1.5cupsgrated Parmesan cheesedivided
3cupsshredded mozzarella cheese
0.25teaspoonsground nutmeg
12sheetsno-boil lasagna noodles
4cupsbaby spinachlightly packed
Instructions
Preparation Steps
Preheat oven to 400°F. Toss the cubed butternut squash with olive oil, 1 teaspoon salt, and 0.25 teaspoon pepper on a sheet pan. Roast until tender and lightly caramelized, about 25 minutes. Reduce oven to 375°F.
Make the sage béchamel: In a large saucepan over medium heat, melt the butter. Add onion and cook until soft, about 5 minutes. Stir in garlic and sage and cook 1 minute until fragrant.
Sprinkle in the flour and cook, stirring, 1 minute. Slowly whisk in the milk until smooth. Simmer, whisking often, until thick enough to coat a spoon, 6 to 8 minutes. Stir in nutmeg and the remaining 0.5 teaspoon salt and 0.25 teaspoon pepper.
Blend 3 cups of the roasted squash with the vegetable broth until very smooth. Stir the puree into the béchamel to make a creamy squash sauce. Reserve the remaining roasted squash cubes for layering.
In a bowl, mix ricotta with 0.5 cup Parmesan until combined.
Assemble the lasagna in a 9x13-inch baking dish: Spread 1 cup squash sauce on the bottom. Arrange a layer of noodles. Dollop one-third of the ricotta mixture, scatter one-third of the spinach and one-third of the reserved squash cubes, then sprinkle about 1 cup mozzarella.
Repeat the layers two more times (sauce, noodles, ricotta, spinach, squash, mozzarella). Finish with a final layer of noodles, the remaining squash sauce, remaining mozzarella, and the remaining 1 cup Parmesan.
Cover the dish tightly with foil (spray the underside with nonstick spray to prevent sticking). Bake at 375°F for 25 minutes.
Remove foil and bake until bubbling and golden in spots, 15 to 20 minutes more. Let rest 10 minutes before slicing so it sets.
Slice and serve warm. Garnish with extra chopped sage or cracked pepper if desired.
Notes
Make ahead: Assemble up to 24 hours in advance, cover, and refrigerate. Add 10 minutes to the covered bake time. For a gluten-free version, use gluten-free no-boil noodles and a gluten-free flour blend for the sauce.